Where Are CB1 and CB2 Receptors Located in the Body?
CB1 receptors are most plentiful in the brain and central nervous system, driving the 'high' associated with cannabis. CB2 receptors are concentrated in the immune system, inflammation, and gut. Both play roles in pain perception, mood, and homeostasis.
Where Else Are They Found?
CB1 receptors also appear in the lungs, liver, and kidneys. CB2 receptors are found in the peripheral nervous system and spleen. These widespread locations explain cannabis's diverse effects on health and wellness.
Endocannabinoid System Receptors Explained: CB1, CB2, and the Rest
How Do They Function?
When cannabinoids bind to these receptors, they trigger responses like pain relief or appetite changes. This interaction influences how cannabis affects different body systems, making location key to its therapeutic potential.